Sufentanil

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Efficacy

Analgesic Effect - Sufentanil has a better dose-effective relationship than other fentanil derivatives.

Source: Nach James (1994)
Note: Sufentanil dose 1nmol/kg ≈0.58ug/kg

Pain Threshold Current - Sufentanil produces statistically greater and longer-lasting increases in pain threshold current than fentanyl.

Source : Bailey P et al, ANESTH ANALG 1990;70:8-15

Hypnotic Effect – Thiopenthal requirements are less for Sufentanil than for Fentanyl for induction of sleep.

Source: Anesthesiology 1989; 70:26-30

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