 |
Sufentanil
|
Sufentanil
Prescribing Information
Guidelines for Clinical Use
| Induction of Anesthesia: |
 |
Loading doses: 0.25-2 µg/kg |
Maintenance of Anesthesia: |
| |
Additional boli: 0.03-0.15 µg/kg |
| |
Infusion rate: 0.2-1.5 µg/kg/h |
Note: Effective plasma concentrations 0.5-3ng/ml, |
| |
Threshold plasma concentration for ventilation < 0.2ng/ml |
| |
Infusion should be stoped 45 min before the end of surgery |
| |
No bolus administration within 45 min before extubation |
|
- Total intravenous anesthesia (TIVA/TCI) – Combination of propofol and sufentanil; Extubation immediately after surgery
| Induction of Anesthesia: |
 |
Sufentanil-TCI: Cp=2ng/ml—›
Ce=0.3ng/ml—›
Cp=0.5ng/ml.
Propofol-TCI: Cp=3-5ug/ml,"LOC",
Rocuronium: 0.6mg/kg
2min later Intubation
Before cutting bark:
Sufentanil: Cp=0.5ng/ml
Propofol: Cp=3-5ug/ml Loading doses: 0.25-2 µg/kg |
Maintenance of Anesthesia: |
| |
TCI-TIVA
Sufentanil: Cp=0.2-0.5ng/ml;
Propofol:Cp=3-5ug/ml. |
|
Source : Combination of Propofol and Sufentanil TCI for total intravenous anesthesia. Beijing Chao-Yang Hospital, Wu Qiwei, Yue Yun.
Patient Controlled Intravenous Analgesia (PCIA)
 |
- Loading dose : 5μg (infusion after extubation) loading dose
- Compatibility drug : Sufentanil 150μg+0.9%NS to 200ml
- Background dose : 3ml/h
- Single dose : 2ml
- Lockout time : 30min
|
|
Source: Administration doses from Southern Hospital
Patient Controlled Epidural Analgesia (PCEA)
| |
Chest post-op.1 |
Abdomen post-op. 2 |
gynecology post-op.1 |
orthopedics post-op.1 |
| Compatibility |
Suf. 0.6μg/ml+0.125%Rop. |
Suf.0.5μg/ml+0.12%Rop |
Suf. 0.4μg/ml+0.125%Rop |
Suf. 1.25μg/ml+0.125%Rop |
| Loading dose |
5ml |
---- |
5ml |
5ml |
| Background dose |
2ml/h |
4ml/h |
2ml/h |
4ml/h |
| Single dose |
3ml |
2ml |
3ml |
2ml |
| Lockout time |
30min |
20min |
30min |
30min |
| Analgesia time |
48h |
48h |
48h |
48h |
| Total amount(ml) |
135.70±21.44 |
203.41±22.68 |
134.96±23.584 |
199.75±5.994 |
|
1.Beijing Chao-Yang Hospital; 2. Peking University First Hospital
< Previous | Next >
|
 |