![]() | 下载舒芬尼®手册 | ![]() | ![]() | 下载舒芬尼®产品说明书 | ![]() | 打印产品资料 |
安全性
持续输注 –舒芬太尼l静脉持续输注无蓄积.
Sources: Anesthesiology (1991) Jan; 74(1):53-63
Glass PSA, Pharmacology of remifentanil. European Journal of Anaesthesiology, 1995, 12(Suppl. 10):73-74
呼吸抑制 – 舒芬太尼对循环系统影响小,呼吸抑制作用比芬太尼弱.
Source : Bailey PL, Streisand JB, East KA, et al. Differences in magnitude and duration of opioid-induced respiratory depression and analgesia with fentanyl and sufentanil. Anesth Analg 1990; 70:8-15.
恶心和呕吐 – 与芬太尼相比,舒芬太尼在发挥优异镇痛作用的同时,严重恶心和呕吐的发生率低.
PCEA | 芬太尼组 | 舒芬太尼组 |
药物配伍 | 0.12% 罗哌卡因+2ug/ml 芬太尼 | 0.12% 罗哌卡因+0.5ug/ml 舒芬太尼 |
剂 量 | 背景剂量:4ml/h, 自控单次剂量: 2ml, 锁定时间: 20min |
Source: Yao Tong, Wu Xin-Min, Yang Shun-Wei. Postoperative PCEA with Sufentanil plus ropivacaine. Chinese Journal of Pain Medicine 2005, 11, (3)
肝外代谢 – 原位肝移植(OLT)患者舒芬太尼的总清除率显著高于肝脏清除率.
Source: Marc Raucoules, Michel Kaidomar, et al., Hepatic disposition of alfentanil and sufentanil in patients undergoing orthotopic liver transplantation. Anesth Analg 1997; 84:1019-24