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Efficacy
Analgesic Effect - Sufentanil has a better dose-effective relationship than other fentanil derivatives.
Note: Sufentanil dose 1nmol/kg ≈0.58ug/kg
Pain Threshold Current - Sufentanil produces statistically greater and longer-lasting increases in pain threshold current than fentanyl.
Source : Bailey P et al, ANESTH ANALG 1990;70:8-15
Hypnotic Effect – Thiopenthal requirements are less for Sufentanil than for Fentanyl for induction of sleep.
Source: Anesthesiology 1989; 70:26-30
